Setting up Guitar Rig 4 for a SoundBlaster Audigy 2 ZS sound card.
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 Click on the image below to see a larger image
I use a custom made stereo tube pre amp to record Guitar rig
The pre amp is shown in the picture with a red rectangle around it
Here's a link to the pre amp I built

The guitar goes into the input jack and then the signal is split to go into each tube preamp.
The signal comes out of each tube pre amp on the rear of the pre amp
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In Guitar Rig, go to File then Audio and MIDI settings to make your audio setups.
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Click on the Audio tab
The Driver is set to ASIO.
The device is set to Creative ASIO
I Use the Creative ASIO drivers, not ASIO4all generic drivers
I set the sample rate to 48000
The latency figures are displayed at the bottom based on what you have selected up above
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Click on the Routing tab and then click on the Inputs button.
I have selected Analog Mix left and right for my inputs.
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Now click on the Outputs button.
I have selected Wave as output 1 and 2, Left and Right.
Click on the MIDI tab at the top. Set MIDI to off if you do not need to use Midi
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If you have a midi interface you want to set up, click on the Midi tab
I use a M-Audio uno for a USB my midi interface
If your midi interface is hooked up and running correctly, click on the status and turn it on
I use a Behringer FCB1010 to control guitar rig
You can see info about the FCB1010 here.
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Click on the image below for a larger image
Guitar Rig 4 scren shot
You need to set all the levels correctly in order to get a strong signal without clipping into the red
You set each level in the order it travels through Guitar rig, from start to finish

Set the levels by strumming your guitar hard
Set the Input level - Top Left of screen shot
Set your cabinets & mics - middle of screen shot
Set the pre-set out volume - Bottom of screen shot
Set the output level - Top right of screen shot

There are other settings that you may have to make also
Don't forget that windows has volume slider settings in the Control panel - Sounds and Audio devices
I am using WinXP. It may be different in other windows versions
The level coming out of your sound card may need adjusting
Also, I am feeding a signal from my pre amp into my sound card via the line in jack
I have to set the level of that input also in the windows control panel volume
Go to this page for Windows mixer info